In MADNESS: Project Nexus, they are introduced in Story Mode's stage Deep Storage and are all armed with laser-based weaponry, typically the Laser Pistolettes with the occasional Laser Rifles. In Madness: Project Nexus (Classic), the Nexus Scientists appear to be unarmed civilians and are neutral to Christoff, although some of them had maybe been caught in the crossfire between him and Phobos' agents.